Cerebral perfusion SPET correlated with Braak pathological stage in Alzheimer's disease

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Cerebral perfusion SPET correlated with Braak pathological stage in Alzheimer's disease.

Reductions in regional cerebral perfusion, particularly in the posterior temporo-parietal lobes, are well recognized in Alzheimer's disease. We set out to correlate perfusion changes, using (99m)Tc-HMPAO single photon emission tomography (SPET), with the pathological stage of Alzheimer's disease. The 'Braak stage' of the distribution of neurofibrillary pathology in post-mortem brains was used t...

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ژورنال

عنوان ژورنال: Brain

سال: 2002

ISSN: 1460-2156

DOI: 10.1093/brain/awf185